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The primary cause of tingling and frequent swelling in leg is vitamin deficiency or protein loss. Kidney dysfunction may be another factor causing this problem. In healthy individuals, this may be a sign of Vitamin B12 deficiency. Calcium, protein and Vitamin B12 supplements must be taken as suggested by the doctors to manage this problem well.Dr. Arun Kumar, consultant physician and diabetologist from Bengaluru, Karnataka, speaks on the causes and management of frequent swelling and tingling in the legs.